Gilmore used a very distinct sound in the solo of comfortably numb, along with the background heavy reverbed distortion in brick in the wall, whatshall we do to.........climbing up the string.
Here is a patch with the tap tempo just right for brick, just bring it up or down to blend. The distortion is set as well so use the fx on/off mode to go from clear to metal. The chorus is there for the solo of comftblynumb. Check it in headphones.
The distortion is also very close to a rockman tone. Tweak it and ye shal find.